Pharmacogenomics: Social, Ethical, and Clinical Dimensions
نویسندگان
چکیده
منابع مشابه
Ethical considerations in clinical pharmacogenomics research.
In recent years there have been unprecedented advances in our understanding of the involvement of genetic polymorphisms in the response to drug therapies. Polymorphisms have been identified that lead to variable patient responses to several medications including cardiovascular, psychiatric, anti-infective and analgesic therapies. The potential for the development of customized, genotype-based t...
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Pharmacogenetics offers the prospect of an era of safer and more effective drugs, as well as more individualized use of drug therapies. The effect of human genetic variance on responses to therapy will influence drug-development clinical trials and the use of products in clinical practice. It also promises to raise new ethical challenges, in particular in the fields of research and therapy. Las...
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It is timely to consider the ethical and social questions raised by progress in pharmacogenomics, based on the current importance of pharmacogenomics for avoidance of predictable side effects of drugs, and for correct choice of medications in certain cancers. It has been proposed that the entire population be genotyped for drug-metabolizing enzyme polymorphisms, as a measure that would prevent ...
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ژورنال
عنوان ژورنال: Journal of Medical Ethics
سال: 2004
ISSN: 0306-6800
DOI: 10.1136/jme.2003.004960